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Saudi Journal of Oral and Dental Research (SJODR)
Volume-10 | Issue-10 | 432-438
Review Article
Vitamin D Supplementation and Dental Implant Osseointegration: A Literature Review
Oubaied GAROUACHI, Omar Al WENZERFI, Chaima ZAIEM, Seif Eddine Ben El MEKKI, Amal FANTAR, Ikdam BLOUZA
Published : Oct. 31, 2025
DOI : https://doi.org/10.36348/sjodr.2025.v10i10.009
Abstract
The aim of this study was to assess the available literature on the efficacy of vitamin D supplementation on the osseointegration of dental implants in humans. The present literature review explores the question: “Does vitamin D supplementation have an impact on dental implant osseointegration?” Relevant publications were identified through electronic searches in PubMed and Google Scholar, covering the period from January 2018 to April 2025, using the MeSH terms: Vitamin D, Dental Implants, and Osseointegration. Only human studies published in English or French were considered. The reviewed literature includes articles such as narrative and systematic reviews, clinical trials, randomized clinical trials, case series, and case reports the electronic search yielded a total of 1,542 articles. Eight articles met the inclusion criteria [2 randomized clinical trials, 2 prospective studies, 1 retrospective study, 1 case report, and 2 literature reviews], comprising clinical data from 316 patients. Vitamin D supplementation may enhance osseointegration, notably in patients with deficiency. More research is needed to standardize supplementation protocols.
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