Introduction: COVID-19 has spread around the world. The objective of this study was to explore clinical features among young patients with COVID-19. Material and methods: Ninety patients with severe cases of COVID-19 infection in Western Chongqing were collected between January 21 and March 14, 2020. Patients were then further stratified into four groups by age: youth (< 39 years); middle-aged (39–48 years), middle-elderly aged (49–60 years), and elderly (> 60 years). Comparison of clinical symptoms, laboratory findings, imaging findings, and treatment effects between groups. Results: 22, 27, 19, and 22 cases were in the youth, middle-aged, middle-elderly, and elderly groups respectively. No significant difference existed between gender or by smoking status among the four groups. The clinical indicators of severe disease in the youth group differed significantly from the other three groups and included the lymphocyte count (p < 0.001), C-reactive protein level (p = 0.03), interleukin-6 level (p = 0.01), chest computed tomography (CT) findings (p < 0.001), number of mild cases (p = 0.02), education level (p < 0.001), and CD4 + T lymphocyte level (p = 0.02) at the time of admission, and the pneumonia severity index (PSI) at the time of discharge (p < 0.001). The complications (p < 0.001) among the youth group were also significantly different from the other groups. Conclusions: The clinical manifestations of young patients are relatively mild. This may be related to higher education levels, prevention awareness, and willingness to accept prevention and control of the COVID-19 epidemic among the population in addition to good immune function.