Maxillary lateral incisor agenesis is a common dental anomaly with significant esthetic and functional repercussions. This case report describes a 17-year-old female patient presenting with bilateral agenesis of the maxillary lateral incisors (teeth 12 and 22), managed through orthodontic treatment using the Roth technique with space opening, followed by implant-prosthetic rehabilitation. The treatment outcome demonstrated a significant improvement in esthetics and function. The discussion compares possible therapeutic approaches: space closure versus space opening, and implant-supported versus resin-bonded bridge rehabilitation.