Bisection/bicuspidization is the separation of mesial and distal roots of mandibular molars along with its crown portion, where both segments are then retained individually. A multidisciplinary treatment procedure for such clinical situations that includes restorative dentistry, endodontics, periodontics, and prosthodontics is necessary to preserve the teeth in whole or in part. These teeth can act as independent single units of mastication or as abutments in simple fixed bridges. In this case report in contrast to the common option of extracting the natural tooth, an alternative treatment option is selected for molars with extensive decay that threatens tooth loss. Therefore, this option should be discussed with patients when deciding on a course of treatment, and it may be a good substitute for extraction and implant therapy, particularly in cases of advanced endo-perio lesions.