Background: Chest pain is a prevalent complaint in emergency departments (EDs) and is associated with significant clinical decision-making challenges. The HEART score is a validated tool used for risk stratification of patients with suspected acute coronary syndrome (ACS). Objective: This study evaluates the effectiveness of the HEART score in risk stratification and patient outcomes at Northern Emirates Hospital, UAE. Methods: A retrospective analysis was conducted on 79 patients who presented with chest pain at Northern Emirates Hospital in January 2021. From the available date in patient record, the patients were classified into three risk categories based on the HEART score, and their actual dispositions were compared. Results: Of the 79 patients, 70.8% had a low HEART score (0–3), 25.3% had a moderate score (4–6), and 3.7% had a high score (>7). Discharge rates were 83.9% for low-risk, 70% for moderate-risk, and 33% for high-risk patients while the actual major adverse cardiac event (MACE) rates available from available data were 0%, 15%, and 66.6% for low, moderate, and high-risk patients, respectively. Conclusion: If used, the HEART score can useful in effectively stratifying chest pain patients, aiding in decision-making regarding discharge and admission. Its implementation in EDs could enhance patient care and resource allocation.