This study examines the causal influence among Innovative Investments and the productivity of manufacturing firms in Nigeria (2010-2023). Manufacturing output was utilised as measure of production of manufacturing firms, while Investments on Research & Development (IRD), Investments on New Equipment & Technology (INET), likewise Investments on Employee Skills & Knowledge Development (IESKD), were utilised as proxies of innovative investments, with their data sourced from the annual reports and accounts of 15 selected manufacturing firms quoted in the Stock Exchange Group. The structural equation was estimated utilising the Pairwise Granger Causality technique. The Pairwise Granger Causality results, reveal that only Investments on Research & Development, substantially promote manufacturing output in Nigeria, while manufacturing output substantially supports INET. Therefore, the study concluded that only investments on employee investments on research and development among the selected elements of techno-innovative investments strongly determine the promotion of manufacturing output in Nigeria. Thus, the study recommended that: Research and Development departments of manufacturing firms should embark on increasing investments on R&D that only align with both short and long-term goals of their firms, capable of yielding remarkable results. Also, the manufacturing firms should priorities investments on either to make or acquire new equipment and machines capable of boosting the production. In addition, the personnel department should intensify the development of employees with relevant productive skills and knowledge.