Haya: The Saudi Journal of Life Sciences (SJLS)
Volume-10 | Issue-01 | 1-7
Original Research Article
Moringa oleifera Total Leaf Extract on Anthropometric and Hematological Parameters in Anemic Rats
Mohamado Ouedraogo, Aboubacar Coulibaly, Amani Jean Paul, Bleyere Nahounou Mathieu
Published : Jan. 3, 2025
Abstract
Study aims to evaluate the evolution of anthropometric and hematological parameters in anemic rats treated with an aqueous extract of Moringa oleifera leaves. Seventy rats aged 8 to 16 weeks were divided into seven groups of ten rats each, including five males and five females. Various doses of the aqueous extract (200 mg/kg, 400 mg/kg, 800 mg/kg, and 1600 mg/kg) were administered in comparison with a positive control group and a group treated with RanferonĀ®. Treatments were administered from day 3 to day 14, with blood samples taken on days 1, 3, 7, and 14. Anemia was induced by injecting 40 mg/kg of phenylhydrazine twice a day for two days. The samples allowed for the determination of red blood cell count, hemoglobin levels, hematocrit levels, mean corpuscular volume, mean corpuscular hemoglobin concentration, and platelet count. The results showed a correction of anemia by the aqueous extract of Moringa oleifera leaves from the seventh day of the experiment, unlike the positive control group.