This study was designed to examine the relationship between organisation design and organisational effectiveness in the Nigerian construction industry. The population of this study was the entire managerial staff population of Julius Berger Nigeria Plc and Setraco Nigeria Limited, both construction companies in Nigeria. The study adopted the survey research design and copies of structured questionnaire were administered to a sample of 341 respondents. Proxies for organisation design were drawn from Kates and Galbriath “Star Model” of organisation design. Descriptive statistics were used to analyse the data, while simple linear regression analysis was used to test the hypotheses formulated for the study. The findings of this study indicate that the five elements under study have strong positive relationship with organisational performance. Consequently, it is recommended that management of organisations in the Nigerian construction industry should consider all five elements when designing or re-designing their organisation.