Caste system is a major feature of Indian society. Caste of a citizen affects his/her social, political and economical behavior. The researchers tried to find out the role of gender and caste of the employee in his/her job satisfaction. For this purpose primarily 575 primary school teachers were selected. Out of which 90 teachers (45 male and 45 female) of General category, 90 teachers (45 male and 45 female) of Other Backward category and 90 teachers (45 male and 45 female) of Scheduled caste category were selected. Thus finally 270 teachers were selected. Teachers‟ Job Satisfaction Scale (TJSS) was used to collect the data. The results of the two-way ANOVA showed a significant interactional effect of caste category with gender on job satisfaction while there was a significant difference among the caste category on job satisfaction. However, there was no significant difference between male and female teachers on job satisfaction.