This paper proposes a new high-gain Buck-Boost DC-DC converter, specifically designed for micro-grid applications where efficient voltage and power management is crucial. Traditional boost converters, such as those with switched inductors or capacitors, face limitations in voltage gain due to extreme operating cycles, leading to issues like reverse recovery, high conduction losses, and electromagnetic interference. Isolated converters, such as fly-back or push-pull converters, while effective at overcoming these constraints, introduce losses due to leakage inductance and overvoltage. With the rise of micro-grids and photovoltaic (PV) systems requiring high voltage gain due to their low output voltage, the proposed Buck-Boost DC-DC converter stands out for its ability to provide high output voltages while accommodating a wide range of input voltages. The converter is designed to handle input voltages ranging from 7V to 75V and uses pulse-width modulation (PWM)-based control to precisely regulate the output. Additionally, it incorporates advanced protection mechanisms with the LM5050-1, providing reverse input voltage protection and reduced quiescent current (IQ), ensuring enhanced safety and improved energy efficiency. Experimental results show that this Buck-Boost DC-DC converter significantly improves power management in microgrids, offering a reliable solution for renewable energy distribution systems and standalone networks. Its flexibility, robustness, and advanced protection features make it ideal for meeting the needs of next-generation power grids.