Aquaculture industry is a largest industry which provides protein rich food. This industry aims to fulfill peoples dietary needs globally. Purpose of this study was to examine the effects of Moringa oleifera leaf meal (MOLM) on growth, hematological and mineral composition of Catla catla fingerlings. An experiment with 180 days feeding trials was conducted to examine the efficacy of MOLM. This experiment was performed according to semi-intensive rearing system to assess the performance of Catla catla fingerlings under MOLM diet. MOLM was used as test ingredient in experimental diets. Five varying levels of MOLM (6%, 12%, 18%, 24% and 30%) were tested to replace fishmeal. For first fifteen days, these fingerlings were placed under laboratory conditions in cemented ponds for acclimatization. When these fingerlings were fully acclimatized, then they were divided into six study groups. Among six earthen ponds, total 90 fingerlings were uniformly distributed. So, fifteen fingerlings were nourished in each pond. Data were recorded for various growth, hematological and mineral composition of fingerlings body. Analysis of recorded data revealed that 12% MOLM diet provided highest results for growth parameters as compared to controlled or other experimental diets. Highest results for hematological and body mineralization were also found in those fingerlings fed with 12% MOLM diet. In this current study, it was determined that 12% replacement of fishmeal by MOLM enhanced growth, hematological parameters and body minerals of Catla catla fingerlings.