Background: Aligners, commonly used in orthodontic treatments, have shown varying degrees of effectiveness depending on the type of tooth movement required. This systematic review will outline recent findings and updates regarding the predictability of aligners in incisor extrusion and molar intrusion movements. Haut du formulaire. Objective: The purpose of this study was to systematically review the literature and evaluate the predictability of clear aligners in incisor extrusion and molar intrusion movements based on the available evidence. Materials and Methods: A total of three databases (Pubmed, Sciences Direct and Google Scholar) were searched until March 2023, in addition to a manual search in the following journals: the American Journal of Orthodontics and Dentofacial Orthopedics, The Angle Orthodontist, and the European Journal of Orthodontics. Finite elements studies assessing the ability of aligners in achieving incisor extrusion and molar intrusion movements published during the last 10 years in English were eligible to be selected. Study selection and data extraction were undertaken independently by two reviewers. Risk-of-bias (RoB) assessment was evaluated using the Methodological Quality of Single Subject Finite Element Analysis. The reporting of this review was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Results: Four pertinent articles were incorporated into the analysis, all of which are finite element studies. Among these, three studies assessed the efficacy of aligners in achieving incisor extrusion, while one solely examined their predictability in molar intrusion. The risk of bias was categorized moderate in all studies. All these studies have agreed that attachments are essential for achieving incisor extrusion and molar intrusion movements. In fact, the position of the attachment has a greater influence on the amount of movement than its shape. Conclusion: The use of attachments has proven to be crucial for successfully achieving vertical movements with aligners. Horizontal rectangular palatal attachments are essential for incisor extrusion, while a combination of buccal and palatal attachments is necessary for molar intrusion.