Background: Discharge Against Medical Advice (DAMA) is considered one of the worldwide concerns of the healthcare sector. DAMA is the condition when the patient or caregiver in the case of pediatrics, leaves the hospital against the recommendation or agreement of the treating physician. This study aims to assess DAMA prevalence among pediatrics in two tertiary hospitals in Saudi Arabia and explore demographic data related to DAMA in pediatric patients. Methodology: A retrospective study was conducted in two tertiary hospitals (KFMC, Dr. Suliman Al-Habib) using the medical records of all DAMA from 2021 to 2022. All analyses were performed using SPSS. Descriptive statistics and chi-square were used. P-values of less than 0.05 were statistically significant for all analyses. Result: The total number of discharges among the two hospitals was 10,707, with 264 DAMA cases. The prevalence of DAMA was found to be 2.47%. Most DAMA cases had a more extended stay at the hospital, exceeding 22 days, with a prevalence rate of 5.14. There was no significant difference in DAMA cases between males and females, with rates of 2.46% and 2.48% respectively. Conclusion: The study found that the rate of DAMA in two tertiary hospitals is within the range in Saudi Arabia. Also, DAMA was linked to more extended hospital stays, significantly impacting patients and the healthcare system.