The sphenopalatine ganglion has maximum number of neurons in the calvarium that are not situated within the brain. In the sympathetic, parasympathetic and sensory nervous system it’s the largest and most superior ganglion. SPG block in conjunction with topical anaesthetic and radiofrequency ablation is currently advised for the treatment of trigeminal neuralgia, cluster headaches, migraines, and persistent idiopathic facial discomfort. The block of SPG is also known as “the miracle block”. The sphenopalatine ganglion block is a simple and safe procedure which can be used for eliminating acute or chronic pain and reduces the episodic recurrence of the pain.