Satisfaction is considered as a motivation to help individuals who are not persistent enough to fully perform physical education exercises. However, the effect of satisfaction on fitness development has not been determined, especially for non-sport students. The purpose of this study was to find out the effect of female students' satisfaction on general physical fitness at Saigon University. 1007 female student were volunteered and selected who divided randomize in two groups (experimental and control). The solutions to improve satisfaction was selected and applied to experimental group, while control group do not apply the solution and practice according to a predetermined 15-week training program. The one-way ANCOVA algorithm was used to assess the difference in the general fitness level of female students in the pre- and post-experiment stages between the experimental and control groups. The results indicated that there was difference in the general fitness level of female students between the group that applied the solutions and the control group in the study. Further research is needed to be able to clearly assess the factors affecting the physical development and satisfaction in different groups of subjects in terms of age, gender, higher training level and in different specialized sports group.