Breast cancers constitutes a significant health problem globally, and the pursuit of powerful early detection techniques remains paramount. This study investigates the potential for early prediction of breast cancer among younger females inside the Najran place of Southern Saudi Arabia through the use of genetic screening profiles. The study aims to elucidate genetic markers related to breast cancer susceptibility in this precise demographic, imparting insights into the disorder's early detection and potential preventive measures. A complete literature assessment establishes the modern-day know-how of breast cancer etiology, genetic factors, and screening techniques, highlighting gaps in know-how concerning the genetic profile of young females in Najran. Methodologically, a cohort of younger females will go through genetic screening protocols, coupled with designated clinical checks, enabling the identity and analysis of genetic markers related to breast cancer predisposition. Statistical evaluation may be hired to correlate recognized genetic variants with the threat of growing breast cancer, bearing in mind the construction of predictive fashions. Findings from this research keep massive promise in advancing personalized medicinal drugs and informing focused screening packages, thereby contributing to the early detection and prevention techniques precise to the young girl population within the Najran place of Southern Saudi Arabia.