Background: Electronic Health Record (EHR) systems have been implemented globally to enhance healthcare delivery. In Saudi Arabia, the adoption of EHRs has rapidly increased in recent years, yet little is known about the experiences of healthcare professionals (HCPs) with EHR implementation in this context Aim: This qualitative study aims to explore the experiences of HCPs in Saudi Arabia before and after the implementation of EHR systems, with a focus on understanding the challenges and benefits associated with this transition. Methods: Semi-structured interviews were conducted with a purposive sample of HCPs from various healthcare settings across Saudi Arabia. Interviews were audio-recorded, transcribed verbatim, and analyzed using thematic analysis to identify patterns and themes related to HCPs' experiences with EHR implementation. Results: Analysis of the interviews revealed several key themes related to HCPs' experiences before and after EHR implementation. Before implementation, HCPs expressed concerns about workflow disruptions, technical challenges, and resistance to change. However, after implementation, many HCPs reported improvements in information accessibility, care coordination, and patient outcomes. Despite these benefits, challenges such as increased documentation burden and decreased face-to-face interaction with patients were also identified. Conclusion: The findings of this study highlight the complex and multifaceted nature of EHR implementation in Saudi Arabia. While the transition to EHRs presents both challenges and opportunities for HCPs, it is crucial to address concerns related to workflow optimization, training, and support to ensure successful implementation and maximize the benefits of EHRs in improving healthcare delivery in the Saudi context.