Background: The integration of digital tools into clinical practice holds significant promise for enhancing chronic disease management, yet little known about healthcare provider attitudes towards this integration, particularly in the context of Riyadh, Saudi Arabia. Aim: This qualitative study aimed to explore healthcare provider attitudes towards the integration of digital tools into clinical practice for chronic disease management in Riyadh, Saudi Arabia. Methods: Semi-structured interviews conducted with healthcare providers from various healthcare settings in Riyadh. Purposive sampling employed to select participants, and data were analyzed using thematic analysis to identify key themes and patterns. Results: 33 healthcare professionals were interviewed. Participants expressed mixed attitudes towards the integration of digital tools into clinical practice for chronic disease management. Perceived benefits included improved patient outcomes, enhanced efficiency of care delivery, and increased patient engagement. However, challenges such as technological barriers, resistance to change, and concerns about data privacy and security were also reported. Factors influencing digital tool adoption included organizational support, training needs, and perceived usefulness. Conclusion: The findings highlight the complex attitudes and considerations surrounding the integration of digital tools into clinical practice for chronic disease management among healthcare providers in Riyadh. Addressing barriers and enhancing support mechanisms are crucial for promoting successful adoption and utilization of digital health technologies in healthcare settings. These insights can inform policy, practice, and research initiatives aimed at optimizing chronic disease management through the effective integration of digital tools.