Scholars International Journal of Traditional and Complementary Medicine (SIJTCM)
Sch Int J Tradit Complement Med.
Dr. Dilip Kr. Goswami
Scholars Middle East Publisher
Country of Origin:
“Scholars International Journal of Traditional and Complementary Medicine” ISSN 2616-8634 (Print) & ISSN 2617-3891 (Online) is a Monthly, peer reviewed, open access, Journal published by published by “Scholars Middle East Publishers”, Dubai, UAE. This Journal publishes Original Research Articles, Review Articles, Mini-Reviews, Short Communications, Case Reports and Case Series, Essays within the whole traditional medical systems.
Scope of Journal
The scopes of “Scholars International Journal of Traditional and Complementary Medicine” includes all the areas of research activities and findings in all fields of Traditional & Alternative Medical Sciences like Ayurveda, Naturopathy, Homeopathy, Herbal Medicine, Holistic Therapy, Music therapy, Traditional Chinese medicine, Holistic therapy, Acupuncture, Yoga, Unani, etc.
Dr. Dilip Kr. Goswami
Associate Professor Dept. of Agada Tantra and Vidhi Ayurveda Govt. Ayurvedic College Jalukbari, Guwahati – 781014 Kamrup (Assam), India Email: firstname.lastname@example.org
Dr. Khaled Nabih Rashed
National Research Centre, Pharmacognosy Department, Dokki, Giza , Egypt
Dr. Sandeep Madhukar Lahange
Assistant Professor Department of Sharir Rachana National Institute of Ayurveda, Jaipur, Rajasthan, India
Dr Jithesh M
Associate Professor Department of Kayachikitsa & PG Studies in Manas roga Vaidyaratnam PS Varier Ayurveda College, Kottakkal Kerala, India
Dr. Kalpana Patni
Asst. Professor, State Ayurvedic College and Hospital. Lucknow, Uttar Pradesh (India)
Dr. Roshanak Ghods
Assistant Professor Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran & School of Persian Medicine, Iran University of Medical Sciences, Tehran, Iran
Dr Madhavi Seetha
Associate Professor & H.O.D Panchakarma M.S.M. Institute of Ayurveda , B.P.S. Mahila Vishwavidyalaya, Khanpur Kalan, Sonipat, Haryana-131305 , India
Assistant professor, Department of Shalakya, Tantra, MSM Institute of Ayurveda, Bhagat Phool Singh women university, Khanpur kalan, Sonepat, Haryana, India
Dr Guruprasad K
Associate Professor Dept of Swasthavritta, Sri Jayendra Saraswathi Ayurveda College and Hospital, Nazarathpet, Chennai Tamilnadu, India
Dr. Udaya Ganesh B
Assistant Professor, Dept of Panchakarma, SJS Ayurveda College and Hospital, Nazarathpet, Chennai, India
Dr Rajendra H.M
Associate Professor Sri Jayendra saraswathi Ayurveda College & Hospital, Nazarathpet, Chennai – 600123, Tamilnadu, India
Principal, Professor & Head, Department Of Community Medicine, Government SDJ HomoeopathicMedical College & Hospital, Chandeswar, Azamgarh 276128,UP, India
Mutation in hprt1 Gene or HPRT Deficiency May be a Restricting Progeny of Favipiravir in Covid-19
Muhammad Torequl Islam
Page Numbers : 162-164
DOI : 10.36348/sijtcm.2020.v03i08.001
Favipiravir (FPV), a pyrazine carboxamide derivative (6-fluoro-3-hydroxy-2-pyrazinecarboxamide) is a broad-spectrum anti-viral drug which acts against many species of Arenaviridae, Bunyaviridae, Caliciviridae, Filoviridae, Flaviviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae, Rhabdoviridae, Togaviridae groups. According to the WHO, FPV may be a new hope for the treatment severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and for this it has undergone for a number of clinical trials. However, human hypoxanthine guanine phosphoribosyltransferase (HPRT) is believed to play a key role in its physiological activation process, therefore, the patients having Kelley-Seegmiller syndrome, Lesch–Nyhan syndrome, myocardial ischemia, hyperuricemia, anemia, and phosphoribosyl diphosphate (PRPP) synthetase superactivity due to deficiency to this enzyme might be a limiting factor for the effectiveness of this drug in these types of patients.
Original Research Article
July 28, 2020
Comparison on Phytochemical and Physico-Chemical Parameters of Ocimum sanctum Linn Grown in Different Locations of Sri Lanka
H. R. D. Fonseka, L. D. A. M. Arawwawala, W. M. S. S. K. Kulathunga
Page Numbers : 157-161
DOI : 10.36348/sijtcm.2020.v03i07.005
Objectives: To compare the phyto-chemical and physico-chemcial differences between green leaves monotype (MT1) and purple leaves monotypes (MT2) of Ocimum sanctum Linn grown in selected provinces of Sri Lanka. Methods: Essential oil was extracted by hydro-distillation using Clevenger type apparatus and analyzed by Gas Chromatography technique. Physico-chemical investigations were done according to WHO guidelines. Results: Highest amount of essential oil content was present for both MT1 and MT2 of O. sanctum collected from Southern Province. Moreover, methyl eugenol was present in O. sanctum in a range of 0.2 – 66% and compared to the MT1 methyl eugenol content was higher in MT2 of O. sanctum collected from all selected provinces. The highest percentage of eugenol was contained in MT2 of O. sanctum and there is no significant dependency of the location. Further, it is very interesting to note that percentages of germacrene- D and β-elemene were both higher in MT2 of O. sanctum in WP and SP respectively. However, there was no significant difference in terms of total ash or water soluble ash or acid insoluble ash between MT1 and MT2 collected from four provinces of Sri Lanka. Conclusion: Overall results revealed that MT2 of O. sanctum collected from SP is more versatile in terms of oil content and chemical constituents.
July 25, 2020
Nigella sativa: A Traditional Remedy for the Prevention of Non-Communicable and Communicable Diseases
Mohammad Asadul Habib, Monia Afroze, Mohammad Farhan Islam, Mohammad Sajid, Akibul Islam Chowdhury, Nadim Ahmed
Page Numbers : 149-156
DOI : 10.36348/sijtcm.2020.v03i07.004
For decades, Nigella sativa has been used as herbal medicine. Thymoquinone is a main ingredient isolated from Nigella sativa and has wide range of pharmacological activities, such as protection from oxidative stress, inflammation and infections. This is also suggested that most of the therapeutic effects of Nigella sativa are because of the presence of thymoquinone that's the most bioactive constituent of the Nigella sativa. The crude and thymoquinone extracted from its seeds and oil are effective against non-communicable diseases (hypertension, diabetes, cardiovascular disease, obesity, cancer, etc.) and communicable diseases (malaria, AIDS, hepatitis C virus, fungal, viral, and parasitic infections etc.). The literature studies were preliminary and scanty; however the results revealed that Nigella sativa (black seed) plants have a possible therapeutic impact for wide range diseases. Such results are encouraging for the incorporation of those plants in treatment of both communicable and non-communicable diseases.
Original Research Article
July 16, 2020
Asparagus racemosus (Willd) of Indian Origin: in Terms of Physico-Chemical, Phyto-Chemical and Nutritional Profiles
Asparagus racemosus Willd belongs to the plant family Asparagaceae and one of the well-known medicinal plants used in indigenous systems of medicine of Sri Lanka. It has abundant medicinal effects such as aphrodisiac, antioxidant, immunostimulant, antihepatotoxic, antibacterial, antidiabetic, anticarcinogenic, antidiarrheal, antiulcerogenic, antioxytocic, etc. Local suppliers for A. racemosus cannot meet the country requirement and therefore, mainly depends on imported A. racemosus grown in India. Therefore, an attempt was taken to evaluate the physico-chemical, phytochemical and nutritional profile of A. racemosus grown in India. Results revealed that 6.2 0.1% of total ash, 1.9 0.0% of water-soluble ash and 1.7 0.0% of acid insoluble ash were contained in roots of A. racemosus grown in India. Total phenolic content, total flavonoid content and total saponin content were 14.0 ± 0.1 mg gallic acid equivalents/g of extract 7.1 ± 0.2 mg quercetin equivalents/g of extract and 4.5±0.2 % respectively for A. racemosus grown in India. Twelve prominent spots bearing Rf values of 0.07, 0.09, 0.12, 0.20, 0.25, 0.28, 0.36, 0.48, 0.54, 0.71, 0.89 and 0.93 were present in Indian origin A. racemosus. Heavy metals such as Hg, As, Cd and Pb and microorganisms including Staphylococcus aureus, Escherichia coli, Coliforms, Salmonella and yeast and moulds were not detected in A. racemosus roots. Energy value of A. racemosus grown in India was 22 kcal/100g. In conclusion, present study illustrates a clear idea of physico-chemical, phytochemical and nutritional properties of A. racemosus grown in India.
Original Research Article
July 16, 2020
“Effect of Mind Sound Resonance Technique (A Yogic Relaxation Technique) on Cognitive Functions in Elderly Population”
Dr. Vijaya Kumar PS, Sahana AU, Vaidehi Rangarajan
Page Numbers : 144-148
DOI : 10.36348/sijtcm.2020.v03i07.003
Background: Aging is a normal process in the life of all living beings. It is a multidimensional process of physical, psychological, and social change. Some dimensions of ageing grow and expand over time, while others decline. The study looks at effect of MSRT a yoga technique in elderly to improve cognitive functions like attention, concentration, short term memory and executive functions. Materials and Methods: Elderly subjects were recruited based on inclusion and exclusion criteria (n = 30) for a single group interventional pre-post study design: MSRT (a relaxation technique) was given for a period of 1 month (30 days). The subjects were assessed on day 1 pre and post intervention on day 30 on Six Letter Cancellation Test (SLCT), and Trail Making Test-B (TMT-B). Results: After one month of MSRT practice showed significantly better performance in the SLCT test compared to baseline by Paired sample t test (P < 0.0001) and TMT-B scores (P < 0.0001). Conclusions: The results of this study establish that MSRT can be used as a technique to enhance cognition and prevent cognitive decline in the elderly.
July 8, 2020
Auspicious Offering of Lord Shiva as a Source of Natural Antiviral Compounds against COVID 19: A Review
Offerings of flowers, leaves, fruits, cereals, foods and drinks to the Gods have been spoken about to a great extent in ancient Hindu scriptures such as Puranas and Vedas. These substances also have replete with significant medicinal values. ' Mahamrityunjaya Mantra Japa' means Great Death-conquering Mantra, is a verse (sukta) of the Rigveda. This mantra is addressed to Shiva for warding off death and bestows longevity. Lord Shiva idolizes with some astonishing substances like Bilva Patra, Bhang Patra, Arka Puspa and Ganga Jal in Mahamrityunjaya Mantra Japa'. Medicinal properties like, antimicrobial, antiviral, antifungal, Anti-inflammatory, Analgesic, Anticancer, Antioxidant property of these have been reported by recent researches. In the future, In vitro and In vivo studies on these items of worship show that these may be an answer to non-treatable diseases like autoimmune disorder, viral infection and cancer etc., as these substances have anti-inflammatory, immunomodulation and antimicrobial properties. Exploration of the text of Traditional and complementary medicine might be useful in research of new drug molecules.
Original Research Article
June 30, 2020
Evaluation of the Antidepressant Activity of Griffonia simplicifolia Aqueous Extracts
Bakou Niangoran François, BA Abdoulaye, Diabate D, Atayi E
Page Numbers : 125-130
DOI : 10.36348/sijtcm.2020.v03i06.003
Objective: The present study was designed to evaluate the acute and chronic behavioral and antidepressant effects of aqueous extracts of GS leaves in standardized rats models of depression. Materials and Methods: Aqueous extracts of GS leaves were prepared, and phytoconstituents were determined using appropriate chemical analytical methods. Animals were divided into five groups: The control group received vehicle (saline water 10ml/rat). Amitriptyline (20mg/kg b.w., IP) was used as the positive control or standard group while the treated rats received GS (100, 200, and 400mg/kg body weight i.p). In the acute treatment study, a single dose was administered 30 min prior to testing. For the chronic treatment study, a single dose was administered daily for 14 days. In the chronic dose study, the behaviors of all groups were assessed for antidepressant activity 30 min after the last treatment dose on the 14th day. Different standardized depression models were used for behavioral tests to evaluate the antidepressant activity, such as forced swim test (FST), and tail suspension test (TST) test. Results: The preliminary pharmacological screening with acute dosing exhibited the antidepressant activity of GS, but its antidepressant activity was more enhanced after repeated dosing. In comparison with the acute studies, chronic dose studies displayed a significant antidepressant manifestation in the behavioral patterns when compared to the vehicle controls. Conclusion: The results obtained in this study suggest that aqueous extracts of GS may possess an antidepressant activity.