Saudi Journal of Medical and Pharmaceutical Sciences (SJMPS) | Volume-6;-Issue-05
Original Research Article
May 8, 2020
pH Indicators: A Valuable Gift for Analytical Chemistry
Sajin KA, Anoobkumar KI, Rasa OK
Page Numbers : 393-400
DOI : 10.36348/sjmps.2020.v06i05.001
Analytical chemistry plays a major role in the quality control of various industrial chemical products. The quality and purity of the products are calculated and confined by applying various principles of chemistry. Thus analytical procedures are regarded to be the outcome of the fundamental principles of chemistry and related sciences. Neutralization titrations are common in establishing the quality of various industrial products taking account of the fact that industrial chemicals and products are mainly acids or bases. The results for the titrations performed on sample require sharp and distinct equivalence points that are identified by the use of suitable acid – base indicators. The present work is a review on common pH indicators used for the neutralization titrations in analytical chemistry.
May 16, 2020
Critical N-Acetylcysteine Treatment Evaluation with Acetaminophen Overdose Management, A Case Report
Dr. Ahmed O Alenazi., Dr. Junaid Alam DABIM, Dr. Juned Loharia. J, Dr. Abdulwaheed Shaikh
Page Numbers : 401-404
DOI : 10.36348/sjmps.2020.v06i05.002
Acetaminophen is the most prevalent, deliberately ingested medication in overdose episodes and a key cause of acute liver failure. N-Acetylcysteine (NAC) is used to treat an overdose of acetaminophen. Using NAC may cause rare fatal adverse events which could affect the safety of the patient. Generally, the type and frequency of NAC related events are too minimal to be considered as an adverse reaction. It is necessary to examine the route of administration, method of reaction detection and the nature of the reactions. These events does not preclude patients from receiving this hepatoprotective advantage, particularly in the context of significant acetaminophen ingestion. We present our case and highlight the clinical inference which can be derived from this entity.
Original Research Article
May 19, 2020
“The Management of Scabies Infection among the Outdoor Patients of BIRDEM General Hospital, Dhaka, Bangladesh”
M. Moniruzzaman Khan, Mir Nazrul Islam, Hosney Ara Begum, Md. Kamrul Ahsan
Page Numbers : 405-415
DOI : 10.36348/sjmps.2020.v06i05.003
Introduction: Scabies is a common contagious parasitic dermatosis. Transmission of the mite Sarcoptes scabiei var hominis generally occurs by skin-to-skin contact, but with crusted scabies it may also occur through fomites, such as infected clothing or bedding. Diagnosis is usually clinical. Objective: To find out The Management of Scabies Infection among the Outdoor Patients of BIRDEM General Hospital, Dhaka, Bangladesh. Materials and Methods: Scope and Delimitation of the Study. This study focused the management of scabies. This study was conducted among the OPD patients in BIRDEM hospital. The study was conducted from January to December 2017.The diagnoses of scabies of the potential respondents were based on the set criteria. Only those diagnose clinically with scabies were included in this study. There were no scraping procedures (acarus test) done to confirm the diagnosis of scabies. Other skin diseases aside from scabies were not included in the study. Results: A 2017 updated Cochrane review concluded that management of scabies is based on topical scabicides, mainly 5% permethrin. However, oral ivermectin, although not licensed in many countries, may be useful, particularly for patients who cannot tolerate or comply with topical therapy and in institutional scabies epidemics. Patients should also receive detailed information about the infestation to limit further spreading. Cases resulting from close physical or sexual contact, even without symptoms, should be systematically treated. Hygienic measures should be taken after treatment is completed. Patients should be followed to confirm cure, including resolution of itching, which may take up to 4 weeks or longer. Conclusion: At the end of this study, the researcher was able to arrive at the following Conclusion Scabies is more common where overcrowded conditions prevail; it can affect any individual irrespective of social status, personal hygiene, profession, gender, age or ethic origin. These include increased number of household members, presence of other family members with scabies, overcrowding, poverty and low educational attainment. Children (l-12 yrs.) have the highest incidence of scabies as compared to the other age group.
Original Research Article
May 21, 2020
Ramadan Focused Educational Program among Patients with Type 2 Diabetes
Hind Asbar, Sana Rafi, Ghizlane El Mghari, Nawal El Ansari
Page Numbers : 416-419
DOI : 10.36348/sjmps.2020.v06i05.004
Ramadan is the ninth month of the Islamic calendar during which Muslims must fast from dawn to sunset. Islam exempts ill and weak people from fasting including high risk patients with diabetes, but a number of them fast regardless of medical advice. Ramadan focused education is a key component for patients with type 2 diabetes (T2D). The aim of our study was to assess the knowledge and awareness of type 2 diabetic patients after a Ramadan focused educational program. This cross sectional study was carried out on patients with type 2 diabetes willing to benefit from a Ramadan focused educational program, 2 weeks prior to Ramadan. Data on sociodemographic characteristics, lifestyle habits, physical activity, blood glucose monitoring, hypoglycemia and hyperglycemia management were obtained. After Ramadan, a questionnaire was used to collect information on patients’ knowledge regarding Ramadan education. Results showed that this study included 176 type 2 diabetic patients with a response rate of 62%. The mean age of our patients was 58 ± 8,1 years. The mean duration of diabetes was 4 ± 6 years. Antidiabetic treatment adjustment was done in 69% of patients, 53% of patients were advised not to fast during Ramadan but 35% of them decided to fast anyway. Patients monitored their blood glucose in 68% of cases and 30% of patients were aware of hypoglycemia and interrupted fasting in 6% of cases.
May 23, 2020
Ocuserts: A Novel Formulation Approach in Drug Delivery System
Nida Parveen, Himanshu Joshi
Page Numbers : 420-425
DOI : 10.36348/sjmps.2020.v06i05.005
Eye is the most fantastic creation of God among all the sense organs in human body as it makes us aware of various objects all around us near and far. The eye is one of the most soft and most valuable of all the sense organs and is a challenging subject for topical administration of drug to the eye. Topical application of drug to the eye is the well accepted route of administration for the treatment of various eye disease like conjunctiva, eye flu etc. The eye as a portal for drug delivery is generally used for local therapy in order to avoid the risk of eye damage from high blood concentration of the drug which is not intended. The field of ocular drug delivery system is one of the most interesting and challenging task usually faced by pharmaceutical scientist/researchers. This field has significantly improved over the past 10-20 years.
May 30, 2020
Role of Adrenal Venous Sampling and Radiological Imaging in Primary Hyperaldosteronism: A Case Report
Page Numbers : 426-428
DOI : 10.36348/sjmps.2020.v06i05.006
We present a case of a 63-year-old man who was evaluated for consistent hypokalemia and longstanding uncontrolled hypertension. Iatrogenic hypokalemia was excluded. He underwent a series of laboratory investigations which showed high levels of aldosterone and increased aldosterone/renin ratio. Renal/adrenal ultrasound (US) showed a mass located in the right adrenal gland, which was presumed to be an adenoma. Adrenal Venous Sampling (AVS) was carried out to establish the diagnosis and secretory ability of the mass but the results showed a paradoxical low aldosterone secretion from the adrenal mass. The patient was further investigated with magnetic resonance imagining (MRI), which confirmed the adrenal mass and on the basis of which he underwent laparoscopic adrenalectomy that resulted in the normalization of aldosterone, serum potassium and blood pressure.