Scholars International Journal of Biochemistry (SIJB) | Volume-3;-Issue-07
Original Research Article
July 5, 2020
Study of Micronutrients and Dyslipidemia in T2DM
Sathisha T. G, Rangaswamy R, Bhargavi S. K, Shashiraj H. K, Kavitha B. S, Arifuddin M. K
Page Numbers : 154-158
DOI : 10.36348/sijb.2020.v03i07.001
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder because of absolute or relative deficiency of insulin production by the beta cells of the pancreas. Trace elements like Zinc and copper are known to affect the synthesis, secretion, release and mechanism of action of insulin. Dyslipidemia is an associated abnormality in most of T2DM patients and the underlying mechanism is not resolved well. Estimation of the trace elements and lipid profile in newly diagnosed T2DM patients will help to identify the onset of early oxidative damage and prevent various complications of T2DM. The present case control study incorporated age and sex matched 48 type 2 diabetic patients and 48 apparently healthy adults. Copper was estimated by Di-Br-PAESA method and Zinc by Nitro PAPS method on Chem 7. HDL-C and TGL quantification was done by EM200 Fully auto analyzer by respective kits from manufacturer. The present study showed that trace elements like serum Copper levels were significantly increased (P < 0.001) where as serum Zinc levels were significantly decreased (P < 0.001).At the same time HDL-C was significantly decreased (P < 0.001) and TGL significantly increased (P < 0.001) in diabetic patients in comparison to controls. Abnormalities in trace elements metabolism and deranged lipid profile may add to the increased risk of complications in T2DM. Early estimation of trace elements and supplementation of the same with therapeutic intervention and correction of lipid abnormalities will help to improve the treatment outcome in these patients.
July 8, 2020
A Review on Smoking is Injurious to Health
Ravichandran S, E. Prabhakar Reddy, Aravind C
Page Numbers : 159-162
DOI : 10.36348/sijb.2020.v03i07.002
Tobacco smoke contains numerous compounds, the important substances of medical significance being the carcinogens (such as polycyclic aromatic hydrocarbons), irritant substances, nicotine, carbon monoxide and other gases. Cigerette smoking is a well-known major risk factor for premature mortality due to cancer, cardiovascular disease, and chronic obstructive pulmonary disease. There is also evidence that passive smoking may contribute to atherosclerosis by sensitizing neutrophils, causing their activation and subsequent oxidant-mediated tissue damage. To achieve a meaningful reduction in the burden to society of coronary heart disease, both passive and active cigarette smoking must be targeted. Many children are regularly exposed to cigarette smoke at home or in other environments, such as child-care facilities and schools. The only safe way to protect nonsmokers from exposure to cigarette smoke is to eliminate this health hazard from public places and workplaces, as well as from the home.
July 14, 2020
Treatment Method of Water based on the Magnetic Devices
Nguyen Le Thai, Dang Van Hai, and Trinh Tien Tho
Page Numbers : 163-166
DOI : 10.36348/sijb.2020.v03i07.003
Magneto - Electric Machine, a device based on the principle of electromagnetic radiation in water is used to separate the bonds of compounds in water. Since magnetic treatment has a variety of selective influences on different substances and processes, its application has wide potentials in the practice. This paper presents a research result on the influence of the magnetic field on the water's Total Dissolved Solids (TDS) and Potential of Hydrogen (PH). Then, the experimental results are conducted to show that the fluctuation of the magnetic field affects the concentration of PH and TDS in water.